Learn about the connection between this common comorbidity for your patients with obesity and how it can affect their health
It’s time to make weight loss a priority
In one study, patients 16 years of age and older with an elevated BMI were
to have hypertension1
Obesity can be associated with some common CVD risk factors, including2:
Obesity and its related risk factors can lead to development of cardiovascular diseases, including2-4:
How does obesity affect cardiovascular disease?
obesity-related cardiovascular deaths occurred worldwide in 20155
Obesity can lead to enlarged adipose tissue cells, or adipocytes, which promote low-grade systemic inflammation.6 This can3,7:
Increased adipose tissue can further lead to endothelial dysfunction and serious cardiovascular conditions.7
A 5% to 10% weight loss can improve8:
Obesity is caused by a range of factors
1. Bramlage P, Pittrow D, Wittchen HU, et al. Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled. Am J Hypertens. 2004;17(10):904-910.
2. Powell-Wiley TM, Poirier P, Burke LE, et al. Obesity and cardiovascular disease. Circulation. 2021;143:e984-e1010.
3. Cohen JB. Hypertension in obesity and the impact of weight loss. Curr Cardiol Rep. 2017;19(10):98.
4. Thomsen M, Nordestgaard BG. Myocardial infarction and ischemic heart disease in overweight and obesity with and without metabolic syndrome. JAMA Intern Med. 2014;174:15-22.
5. Afshin A, Forouzanfar MH, Reitsma MB; GBD 2015 Obesity Collaborators. Health effects of overweight and obesity in 195 countries over 25 years. N Engl J Med. 2017;377(1):13-27.
6. Heymsfield SB, Wadden TA. Mechanisms, pathophysiology, and management of obesity. N Engl J Med. 2017;376(3):254-266.
7. Cercato C, Fonseca FA. Cardiovascular risk and obesity. Diabetol Metab Syndr. 2019;11:74.
8. Ryan DH, Yockey SR. Weight loss and improvement in comorbidity: differences at 5%, 10%, 15% and over. Curr Obes Rep. 2017;6(2):187-194.